Authors: Owen M. McDougal
Affiliation:
Title: Deadly Snails, NMR, and the
Abstract: Peptides isolated from the
venom of predatory marine snails of the genus Conus have been found to have
tremendous selectivity and potency for binding to a wide variety of receptors.
Nuclear magnetic resonance (NMR) spectroscopy provides a method for
understanding both the three dimensional structure of these interesting peptides
and also their interaction with receptors.
The role of NMR in understanding biological systems can be extended to
the study of infectious disease. A
sampling of data will be presented to open a discussion for ways that the new
NMR Facility at