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Presentations

National Meetings:

1.  Runquist, J.A., Charlier, H.A., and Miziorko, H.M.  (1994) “Evidence for an Aspartate as Phosphoribulokinase’s Catalytic Base.” The FASEB Journal 8, A1346.

2.  Charlier, Jr., H. A., and Plapp, B. V.  (1999) “Nonhyperbolic Kinetics of Human Liver Alcohol Dehydrogenase g2.”  The FASEB Journal 13, A1441.

3.  Charlier, H.A., Maupin, C.M., and Plapp, B.V. (2002) “Coenzyme Binding by Horse Liver Alcohol Dehydrogenase:  Evaluating the Role of Charge at Position 228.” Division of Biological Chemistry, 224th National Meeting of the American Chemical Society, August 18 – 22, Biochemistry 41, 8968.

4.  Cheney, M., and Charlier, H.A. (2003) “Kinetic Characterization of Carbonyl Reductases From Rabbit Heart.” National Council for Undergraduate Research, Salt Lake City Utah.

5.  Hibberd, A.M., Charlier, H.A., and Serpe, M. D.(2003) “A possible role for -1,3-glucanases in intrusive growth of the nonarticulated laticifer cell”. National Council for Undergraduate Research, Salt Lake City Utah.

6. Cheney, M., and Maupin, C.M. (2003)  “Kinetic characterization of carbonyl reductase activities from rabbit heart cytosol.”  Division of Biological Chemistry, 226th National Meeting of the American Chemical Society, September 7-11,Biochemistry 42, 8594.

7.  Thornock, C., Charlier, H.A., Jr., Olson, R.D., Mercer, W.K., Broyles, T.S., Gambliel, H.A., Cusack, B.J., Shadle, S.E. (2003) “Anthracyclines inhibit calcium release from the sarcoplasmic reticulum and bind directly to calsequestrin.” Division of Biological Chemistry, 226th National Meeting of the American Chemical Society, September 7-11, Biochemistry 42, 8594.

8.  R.D. Olson, H.A. Charlier, C.Thornock, W.K. Mercer, T.S. Broyles, D.R. Olson, H. Gambliel, B. Cusack,S.E. Shadle. (2003) “The calsequestrin inhibitor trifluoroperazine disrupts cardiac musclefunction and inhibits SR Ca2+ release.” 47th Annual Meeting of the Biophysical Society, San Antonio,TX, Biophysical Journal Supplement, February, 84, Number 2, Part 2 of2, 99a.

9.  Susan E. Shadle, Dawn Muhlestein, Nico Cantone, Carissa Thornock, Henry A. Charlier, Jr., Richard D. Olson. (2004) “Anthracyclines Bind to Calsequestrin and Alter Its Calcium Binding Properties.” 48th Annual Meeting of the Biophysical Society, Baltimore, MD, Biophysical Journal Supplement, February.

10.  Wendy K. Mercer, Nico Cantone, Dawn J. Muhlestein, Henry A. Charlier Jr., and Susan E. Shadle. (2005) Anthracyclines affect calcium ion binding to calsequestrin. The 229th ACS National Meeting, in San Diego, CA, March 13-17, 2005

11.  Williams, B., Larson, C.L., Slupe, A., Olson, K., Begic, S., Lee, L., and Charlier, Jr, H.A. (2005) Novel inhibitors of carbonyl reductase. The 229th ACS National Meeting, in San Diego, CA, March 13-17, 2005.

12.  Charlier, Henry A., Slupe, Andrew, Williams, Berea, Larson, Corianton L., Lee, Laura, Warner, Don L., and Peloquin, Jeffrey M. (2005)  “Anthraquinone reduction by human carbonyl reductase.”  Abstracts of Papers, 230th ACS National Meeting, Washington, DC, United States, Aug. 28-Sept. 1.

13.  Slupe, A., Berhe, S., Bakare, O., Luster, C., Charlier, Jr., H.A. (2006) “Pyrazoloquinone substrates and inhibitors of carbonyl reductase” Abstracts of Papers, 231th ACS National Meeting, Atlanta, GA, March 26-30.

14.  Charlier, Jr., H.A., Warner, D., Slupe, A.M., Williams, B.  Ward, L., Couch, A.,  Bakare, O., and  Gerasimchuk, N.N.  (2006) “Human carbonyl reductase: Identifying inhibitors using irrational drug design.” Enzymology and Molecular Biology of Carbonyl Metabolism, 13th International Symposium, Nashville, Indiana, July 11-15, 2006.

15.  Slupe, A.M.,  Luster, C.,  Warner, D.L., and Charlier, Jr., H.A. (2006) “Novel substrates and inhibitors of human carbonyl reductase” 1st Biennial National IDeA Symposium of Biomedical Research Excellence (NISBRE), Washington, DC., July 20 – 22.

16. Berhe, S., Slupe, A., Luster, C., Charlier, H.A., and Bakare, O. (2006) Synthesis and Carbonyl Reductase (CR) Inhibitory Activities of Indazole-4,7-dione Derivatives. Tenth Research Centers in Minority Institutions (RCMI) International Symposium on Health Disparities, San Juan, Peurto Rico, December 13 – 16.

17. Charlier, H.A., Gerasimchuk, N.N., and Ward, L. (2007) Arylcyanooxime inhibitors of human carbonyl reductase. Abstracts of Papers, 234th ACS National Meeting, Boston, MA, United States, August 19-23.

18. Mayer, M.T. and Charlier, H.A. (2008) Binary and ternary complexes involving small molecules and carbonyl reductase. Abstracts of Papers, 235th ACS National Meeting, New Orleans, LA, United States, April 6-10.
19. Flaherty, B., Romano, A., Furnish, J., Slupe, A. M., and Charlier, H.A. (2008) Construction and preliminary characterization of polyhistidine tagged phosphotriesterase. Abstracts of Papers, 235th ACS National Meeting, New Orleans, LA, United States, April 6-10.

20. Ewing, C.K. and Charlier, H.A. (2008) Carbonyl reductase inhibition as a means to increase anthracycline efficacy. Abstracts of Papers, 235th ACS National Meeting, New Orleans, LA, United States, April 6-10.

21. Young, C. R. and Charlier, H.A., Jr. (2009) Determining the role for methionine 234 in substrate recognition in human carbonyl reductase. Abstracts of Papers, 237th ACS National Meeting, Salt Lake City, UT, United States, March 22-26.

22. White, A.B., Ewing, C.K., and Charlier, H.A. (2009) Determining the ability of resveratrol to inhibit human carbonyl reductase activity. Abstracts of Papers, 237th ACS National Meeting, Salt Lake City, UT, United States, March 22-26.

23. Morton, R., Ewing, C.K., Jorcyk, C., and Charlier, H.A., Jr. (2009) Investigating the role of carbonyl reductase in anthracycline drug resistance. Abstracts of Papers, 237th ACS National Meeting, Salt Lake City, UT, United States, March 22-26.

24. Parker, B.A., Coppola, J.M., Charlier, H.A., Jr., and Hill, M.W. (2009) Hydrolysis of parathion in a liquid-liquid biphasic system. Abstracts of Papers, 237th ACS National Meeting, Salt Lake City, UT, United States, March 22-26.

25. Weaver, J.G. and Charlier, H. A. (2010) Chemistry outreach and recruiting at Boise State University: Igniting community interest and sparking student involvement. Abstracts of Papers, 239th ACS National Meeting, San Francisco, CA, United States, March 21-25.

26. Baggs, E.L.., Young, C., and Charlier, H.A. (2010) Development of a recombinant protein expression system for the production of human carbonyl reductase. Abstracts of Papers, 239th ACS National Meeting, San Francisco, CA, United States, March 21-25.

Statewide/Regional Meetings:

1.  Misra, I., Charlier, H.A., Miziorko, H. M.  (1994) “3-Hydroxy-3-Methylglutaryl-CoA Synthase: Evaluation of the Role of Cysteines in Reaction Chemistry.”  Midwest Enzyme Chemistry Conference, Northwestern University, Chicago,IL.

2.  Charlier, Jr., H. A., and Plapp, B. V.  (1999) “Nonhyperbolic Kinetics of Human Liver Alcohol Dehydrogenase g2: An abortive complex pathway.” Midwest Enzyme Chemistry Conference, University of Illinois – Chicago, Chicago, IL.

3.  Charlier, Jr., H. A., and Maupin, C. M. (2001) “Horse Liver Alcohol Dehydrogenase: The Contribution of Lysine 228 to Catalysis.” 43 rd Idaho Academy of Science Meeting, Albertson College of Idaho, Caldwell, ID.

4.  Bjorklund, C., and Charlier, Jr., H. A. (2002) “Expression of Recombinant Human Liver Carbonyl Reductase in Escherichia coli.” 44th Idaho Academy of Science Meeting, BYU Idaho, Rexburg, ID.

5.  Maupin, C. M., and Charlier, Jr., H. A. (2002) “Horse Liver Alcohol Dehydrogenase: Contribution of Charge at Position 228 to Coenzyme Binding”. 44th Idaho Academy of Science Meeting, BYU Idaho, Rexburg, ID.

6.  Maupin, C. M., and Charlier, Jr., H. A. (2002) “Anthracycline Specificities of Carbonyl Reductases from Rabbit Heart.” 44th Idaho Academy of Science Meeting, BYU Idaho, Rexburg, ID.

7.  Williams, B., Larson, C. and Charlier, Jr., H.A. (2005) Inhibitors Of Human Carbonyl Reductase. 47th Annual Meeting and Symposium of the Idaho Academy of Science, April 7-9, 2005.

8.  Slupe, A.M., Lee, L.M. and Charlier, Jr., H.A. (2005) Anthraquinone Substrates of Carbonyl Reductase. 47th Annual Meeting and Symposium of the Idaho Academy of Science, April 7-9, 2005.

Invited Talks:

1995      Invited seminar, “”Evidence Supporting Catalytic Roles for Aspartate Residues in Rhodobacter sphaeroides Phosphoribulokinase.”  Given to the Department of Chemistry at the University of Wisconsin-Stevens Point, Stevens PointWisconsin.

2003    Invited seminar, “Coenzyme binding by horse liver alcohol dehydrogenase: Evaluating the role of charge at position 228.”  Given to the Department of Chemistry at Washington State University, Pullman Washington.

2005    “Talking to Enzymes: Learning to Control Carbonyl Reductase with Small Molecules.”  Seminar given at the Idaho INBRE Summer Research Conference, August, 2005.

2006    “Human Carbonyl Reductase:  Identifying inhibitors using irrational drug design.” Seminar given at the Idaho INBRE Summer Research Conference, August, 2006.