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Graduate Courses

Course Offerings

(as reflected in the 2016-2017 Graduate Course Catalog)

BIOCHEM — Biochemistry

BIOCHEM 510 ADVANCED PROTEIN CHEMISTRY (3-0-3)(S)(Alternate years).
An in-depth study of proteins that focuses on amino acid chemistry, protein structure, protein folding, and protein function. This course will discuss modern methods of protein characterization and the use of bioinformatics in understanding the chemistry/function of proteins. Given the recent developments in the proteomics, several of the high-throughput approaches to identifying proteins assessing function will also be investigated. Students will make extensive use of primary literature. PREREQ: CHEM 322 and CHEM 432 or PERM/INST.

BIOCHEM 511 NUCLEIC ACID METABOLISM (3-0-3)(S)(Alternate years).
An in-depth study of the metabolism of both DNA and RNA at the molecular/mechanistic level. This course will cover the mechanisms DNA replication, transcription, translation, transposition and repair, as well as those for RNA splicing, catalysis, silencing and interference RNA. Bioinformatics approaches and modern techniques for studying DNA/RNA and their interactions with proteins will be discussed. Students will make extensive use of primary literature. PREREQ: CHEM 432 or PERM/INST.

BIOCHEM 512 INTERMEDIARY METABOLISM (3-0-3)(S)(Alternate years).
An investigation into several anabolic, catabolic, and signaling processes in the cell. Special attention will be given to molecular mechanisms and regulation. Students will make extensive use of primary literature. PREREQ: CHEM 432 or PERM/INST.

BIOCHEM 513 ADVANCED ENZYMOLOGY (3-0-3)(S)(Alternate years).
A deeper look into the catalytic and kinetic mechanisms of enzymes. Modern methods for studying enzymes will be included as well as learning strategies for studying steady state and transient enzyme kinetics. Students will make extensive use of primary literature. PREREQ: CHEM 322 and CHEM 433 or PERM/INST.

CHEM — Chemistry

An introduction to project planning, literature assessment, report writing, and data management. PREREQ: Admission to chemistry graduate program.

Atomic structure, molecular structure using valence bond and molecular orbital theories, elementary group theory, transition metal coordination chemistry, acids and bases, descriptive transition and nontransition metal chemistry. PREREQ: CHEM 322 or PERM/INST.

CHEM 507 PHYSICAL ORGANIC CHEMISTRY (3-0-3)(S)(Alternate years).
Mechanisms of organic chemical reactions, stereochemistry, and conformational analysis. The important types of organic reactions are discussed. Basic principles are emphasized; relatively little attention is paid to the scope and synthetic applications of the reactions. PREREQ: CHEM 309 and CHEM 322 or PERM/INST.

CHEM 508 SYNTHETIC ORGANIC CHEMISTRY (3-0-3)(F)(Alternate years).
The scope and limitations of the more important synthetic reactions are discussed within the framework of multistep organic synthesis. PREREQ: CHEM 309 or PERM/INST.

An introduction to the concepts of polymer synthesis, characterization, structure, properties, and basic fabrication processes. Emphasis is on practical polymer preparation, on the fundamental kinetics and mechanisms of polymerization, and on structure-property relationship. PREREQ: CHEM 309 or PERM/INST.

CHEM 510 ORGANIC POLYMER SYNTHESIS (3-0-3)(S)(Alternate years).
A study of the synthesis and reactions of polymers. Emphasis is on practical polymer preparation and on the fundamental kinetics and mechanisms of polymerization reactions. Topics include relationship of synthesis and structure, characterization of polymer structure, step-growth polymerization, chain-growth polymerization via radical, ionic and coordination intermediates, copolymerization. PREREQ: CHEM 309 or PERM/INST.

CHEM 511 ADVANCED ANALYTICAL CHEMISTRY (3-0-3)(F). Stoichiometry involved in separations and instrumental methods of analysis. The course will be flexible in nature to adapt to the varied background of the students. PREREQ: CHEM 322 or PERM/INST.

CHEM 521 QUANTUM CHEMISTRY (3-0-3)(F)(Alternate years).
Formal introduction to quantum mechanics, Dirac notation, angular momentum and operator algebra. Emphasis will be placed on electronic structure theory, reaction mechanisms and the use of modern quantum chemistry theoretical packages. PREREQ: CHEM 322, or PHYS 309 and PHYS 432, or PERM/INST.

CHEM 522 SPECTROSCOPY (3-0-3)(F)(Alternate years).
Concepts and practical usage of modern chemical spectroscopic techniques, including electronic absorption, infrared/Raman, X-Ray/EXAFS, magnetic resonance and magnetic circular dichroism. Emphasis will be placed on the application of these techniques to the structure/function characterization of chemical and biochemical systems. PREREQ: CHEM 521 or PERM/INST.

CHEM 523 CHEMICAL KINETICS (3-0-3)(F)(Alternate years).
A comprehensive study of the role of quantum chemistry and thermodynamics in chemical reactions. Emphasis will be placed on determining reaction coordinates and transition states. Extensive use will be made of modern computational chemical computer programs for calculating potential energy surfaces and transition states. PREREQ: CHEM 322, or PHYS 309 and PHYS 432, or PERM/INST.

Identification of compounds using modern spectrometric techniques. PREREQ: CHEM 309 and CHEM 321.

CHEM 551 BIOINORGANIC CHEMISTRY (3-0-3)(S)(Alternate years).
Exploration of the vital roles that metals play in biochemical systems. Emphasis is on transition metals in biology. Course will focus on structural, regulatory, catalytic, transport and redox functions of bioinorganic systems. PREREQ: CHEM 322 or PERM/INST.

CHEM 552 ORGANOMETALLIC CHEMISTRY (3-0-3)(S)(Alternate years).
An examination of the organometallic chemistry of the main group and transition elements. Topics to include structure and bonding of complexes having pi ligands; transition metal mediated organic synthesis; homogeneous catalysis. PREREQ: CHEM 401 or 501 or PERM/INST.

This course will instruct students on the theory and practice of one- and two-dimensional NMR spectroscopy. Emphasis will be placed on using the NMR spectrometer to solve a variety of chemical and biological problems. PREREQ: CHEM 322, or PHYS 309 and PHYS 432, or PERM/INST.

CHEM 561 INTRODUCTION TO MOLECULAR MODELING AND COMPUTATIONAL CHEMISTRY (1-3-2)(On demand). Overview of modern computational chemistry. Use of computational chemistry tools and their application to problems of chemical and biological interest. PREREQ: CHEM 322, or PHYS 309 and PHYS 432, or PERM/INST.